I am running a 3 way active setup using Pioneer P99RS! Front components are rainbow vanadiums and using audiofrog drivers for the base.. dont have a dedicated subwoofer at this moment.. I have a TRU monoblock and a rainbow vanadium subwoofer which can be added if really needed..
As for the amplification, am using Mosconi AS200.2 for the base and Flux audio 4 channel amplifier (dont remember the model though) for the tweeters and mids...
Another important point is that you need to have a really good installer for doing the installation and more importantly the TUNING!! luckily, we have a great one in Cochin, who is a mad audiophile too.. Make sure you get a good installer...