I have used Lyrita's ICs for at least 7-8 years now and in their various avatars. One of the earlier versions was a cloth shielded copper wire which later has evolved to an enamel coated bare copper strand. I would best describe the sound as airy, open, free-flowing with a very large sound stage. The latest version sounds more refined than the previous ones in my opinion. Pairing of these cables with Lyrita amps is a very good match (doesn't mean that these don't/can't pair well with other gear). I find them to sound honest, if it makes any sense. It emphasizes on the tonal richness of the music content rather than focusing overtly on embellishing them. The enamel on the cables is so thin, I virtually find these to be non-shielded. In my system these sound effortless and less congested.
Whenever I have swapped the Lyrita ICs with any shielded cables (currently, I use the ones Mr. Murthy makes), it changes the tonal balance of the system. The sound becomes a tad heftier, gets me a sense of more weight and bass, the staging constricts and it sounds a bit subdued/muted. Putting back the Lyrita ICs immediately starts giving me much more information in the music, feels less clogged. By no means is it light on bass, rather it provides a more articulated and defined low end which doesn't feel bloated.
One more thing that I can share based on my experience is that since I live in an RFI prone area (2 radio stations in close vicinity), it makes it very difficult to be able to use the Lyrita ICs in the analog part of the chain. Tube phono amps are sensitive to RFI pickup. RFI is random and varies with weather conditions and what not. There are days when I have been able to use Lyrita ICs between my TT-->Phono & Phono-->Pre. But mostly shielded cables do the duty at the analog side of things.
All of this said, these changes are more apparent in more resolving systems. So the mileage may vary. I will try more cables in the future from other renowned brands and be able to draw more comparisons.