If I listen to a solo voice on my entry-level M-Audio monitors, and the voice appears to come from a point in-between the speakers, and definately not from
either speaker --- I have, at fairly low cost, achieved speaker invisibility! And, of course, it happens regularly
That is just stereo imaging, and it's simple: all-other-things-being-equal, if the voice is coming at us with equal volume from each speaker, it will appear to be in the middle. Possibly, with an effort of will, one can overcome the illusion, but it is not easy, because stereo simply takes advantage of how our ears work.
The illusion of stereo is amazingly simple ...and amazingly wonderful. None of us would be on this forum without it.
So I would say that the speakers disappear in almost any stereo system that is wired correctly and not absolutely crippled by speaker position and other room elements.
But the existence of the stereo image (illusion) is only the first element. How does that single voice sound? Does it sound like a voice? Or does it sound like a voice coming out of speakers? If an audience member coughs, do we look around the room to see who it was? Or do we simply place it in the stereo image. If we look around the room, then I guess we can say that the speakers, in fact, the whole system has disappeared.